Published 2023-07-17
Keywords
- Penis,
- Penile induration,
- Penile diseases,
- Surgery,
- Regenerative medicine
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Copyright (c) 2023 香港六合彩开奖结果
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Abstract
Introduction: Peyronie鈥檚 disease (PD) is a common condition that can cause penile curvature and/ or deformities, thereby affecting the male sexual function. The most effective treatment for clinically significative and stable penile curvature due to PD is reconstructive surgery that involves techniques that do not shorten penile length. Among the techniques for the correction of curvature and restoration of penile length, the incision and/or excision of the plaque, followed by reconstruction of the defect with a graft, remains the gold standard. Although several materials have been used as a graft in the treatment of penile curvature due to PD, none have shown results good enough to be considered as the first choice. Herein, we aimed to evaluate the results of the surgical treatment of patients with penile curvature due to PD using a new biograft. Methodology: We performed the surgical management with graft technique in twelve men suffering from penile curvature due to PD. Penile curvature was measured before and one year after the reconstructive procedure. The graft of choice was bovine pericardium graft segment treated with L-Hydro aldehyde-free technology. Erectile function was evaluated by the IIEF questionnaire and penis length was measured by a rigid ruler during a pharmacologically induced erection test. Results: The overall success rate of correction of the penile curvature was 90.9% and the patients鈥� satisfaction rate was 91.7%. No serious adverse events were found and the erectile function was impaired in 18.2% of cases. There was an increase in penile length, ranging from 0.7 to 3.0cm in 91.7% of cases. Conclusion: Correction of penile curvature due to Peyronie's disease using the technique of incision and/or excision of the plaque with an aldehyde-free bovine pericardium graft presents high success rates, both in terms of penile shaft rectification and patient satisfaction. L-hydro bovine pericardium graft is easy to handle surgically, allows a tight anastomosis and does not present serious postoperative complications. Furthermore, it can be used simultaneously with penile implants and appears to play a role in restoring penile length.
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