香港六合彩开奖结果

Vol. 20 No. 2 (2021)
Original Articles

Comparative analysis of methemoglobin, oxygen saturation and hematological parameters in smokers and non-smokers: An observational analytical cross-sectional study

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  • Nathalia R. S. Remigio,
  • Ligia C. A. Cardoso,
  • Tulio C. L. Lins
DOI:

Published 2022-01-04

Keywords

  • Hematology,
  • Tobacco Use Disorder,
  • Blood Physiological Phenomena

How to Cite

1.
R. S. Remigio N, C. A. Cardoso L, C. L. Lins T. Comparative analysis of methemoglobin, oxygen saturation and hematological parameters in smokers and non-smokers: An observational analytical cross-sectional study. BJHBS [Internet]. 2022 Jan. 4 [cited 2024 Oct. 12];20(2):144-50. Available from: /bjhbs/article/view/37

Copyright (c) 2023 香港六合彩开奖结果

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Abstract

Introduction: The formation of methemoglobin (MetHb) occurs through the oxidation of iron in hemoglobin, impair-ing its capacity for oxygen association and deoxygenation. On exposure to oxidizing agents, such as those present in cigarettes, this process may be more frequent, causing an increase in serum MetHb. Objectives: To evaluate and com-pare methemoglobin, oxygen saturation and hematological parameters between smokers and non-smokers. Materials and methods: Observational case-control study with participants classified as smokers and non-smokers, in equal number and gender. Smokers classified as moderate to very high depen-dence degree by the Fagerstr枚m tolerance questionnaire were included. In all subjects, oxygen saturation was assessed using portable pulse oximetry, methemoglobin levels by spectrophotometric method and hematological parameters by an automated analyzer. Parametric (Student鈥檚 T-test) and non-parametric (Mann-Whitney U) tests were performed for comparison of mean values between groups. Results: There were no changes in methemoglobin rates and hematologi-cal parameters, both in relation to clinical reference values and in the statistical difference between groups. The oxygen saturation values were significantly higher in the smoking group, 96.4% versus 94.8% (p = 0.04). Conclusions: Despite the potential deleterious effects of cigarettes, in this study it was found that smoking was not a determinant of changes in methemoglobin rates and hematological parameters, when compared with non-smokers. Further studies are suggested with a robust sampling population, complementary analysis of hematological and physiological factors and verification of comorbidities, in order to elucidate a greater relationship between the presented parameters.

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