香港六合彩开奖结果

Vol. 22 No. 1 (2023)
Literature Review

Impact of zinc supplementation on male infertility: a systematic review

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  • Jean F. de Lima,
  • Nat谩lia V. S. Daniel,
  • Luciana Pietro
Jean F. de Lima
Departamento de Nutri莽茫o, Universidade Paulista Unip. Campinas, SP, Brazil.
Bio
Nat谩lia V. S. Daniel
Departamento de Nutri莽茫o, Universidade Paulista Unip. Campinas, SP, Brazil.
Bio
Luciana Pietro
Departamento de Biomedicina, Universidade Paulista Unip. Campinas, SP, Brazil.
Bio
DOI:

Published 2023-07-17

Keywords

  • Supplementation,
  • Zinc sulfate,
  • Male infertility,
  • Seminal parameters

How to Cite

1.
Jean F. de Lima, Nat谩lia V. S. Daniel, Luciana Pietro. Impact of zinc supplementation on male infertility: a systematic review. BJHBS [Internet]. 2023 Jul. 17 [cited 2024 Oct. 12];22(1):58-67. Available from: /bjhbs/article/view/63

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Abstract

Introduction: According to the World Health Organization (WHO), infertility is defined as a failure in fertilization without any use of a contraceptive method for at least 12 consecutive months, with the individual being of reproductive age and having an active sexual life, where male infertility has been assuming a prominent position. This condition is considered to be of high importance in the contemporary world. Objectives: To systematically review the literature on the impact of oral zinc supplementation on male infertility and to assess whether its intake exerts a therapeutic effect, based on the evaluation of seminal parameters, according to manuals published by the WHO. Methodology: A systematic review was carried out by means of a search, in the English and Portuguese languages, for original articles in the Pubmed, Science Direct, Lilacs and Scielo scientific databases. Results: The intervention groups ranged from 18 to 77 individuals and the control groups ranged from 8 to 113 individuals. Regarding age, the average age of the participants in the studies was 31 years. The daily dose of zinc administered in the trials varied from 66mg to 500mg and its use time ranged from three to six months. In the end, 87.5% of the studies showed positive results on the sperm parameters evaluated after the intervention. Conclusion: The results were mainly attributed to the protective effect that the trace element provided, reducing the lipid peroxidation index of plasma membranes and improving DNA integrity, thus increasing the fertilization capacity.聽

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