@article{Silvia Thees Castro_José Augusto A. Pereira_Eduardo A. R. de Castro_2023, place={Rio de Janeiro - RJ, Brazil}, title={Letter to the editor: The challenge of carbapenem resistance }, volume={22}, url={/bjhbs/article/view/156}, DOI={10.12957/bjhbs.2023.80042}, abstractNote={<p><span data-contrast="none">The global resistance of microorganisms to antimicrobials is one of the biggest public health challenges in recent decades however, among Gram-negative microorganisms, this problem has become very relevant, resulting in a shortage of medicines for the treatment of infections caused by these multi-resistant bacterial agents.</span><span data-ccp-props="{"134245417":false,"201341983":0,"335559731":708,"335559739":0,"335559740":360}"> </span><span data-contrast="none">Knowing the evolution of this resistance, among microorganisms in the hospital environment, is essential for: the projection of resistance in the coming decades, the rational use of antimicrobials and the adoption of measures to minimize their impact in this scenario. </span><span data-contrast="none">The most modern antimicrobial agents, which act on multi-resistant bacteria, are expensive, making their availability and use even more difficult, especially in the public health network in developing countries. However, new drugs for treating multidrug-resistant infections, due to their high cost, are often not available.</span><span data-ccp-props="{"134245417":false,"201341983":0,"335551550":6,"335551620":6,"335559739":0,"335559740":360}"> </span></p>}, number={2}, journal={Ïã¸ÛÁùºÏ²Ê¿ª½±½á¹û}, author={Silvia Thees Castro and José Augusto A. Pereira and Eduardo A. R. de Castro}, year={2023}, month={Nov.} }