@article{F. Silva_F. Mota_de O. Cabra_V. Farias_M. Dimas_S. de Santana_N. M. de Gusmão_A. Nogueira_N. Ramos_de Souza_de S. Leão_G. de Oliveira_S. dos Santos_Mattos-Guaraldi_de Souza_2022, place={Rio de Janeiro - RJ, Brazil}, title={Multiresistance and endemic status of Corynebacterium striatum associated with nosocomial infections: a critical situation in Intensive Care Units and varied wards of a tertiary care hospital, Rio de Janeiro metropolitan area, Brazil}, volume={20}, url={/bjhbs/article/view/34}, DOI={10.12957/bjhbs.2021.63963}, abstractNote={<p>Nowadays, Corynebacterium striatum has been reported as etiologic agent of mild to severe hospital-acquired infections, including patients undergoing endotracheal intubation with fatal outcome. A continuous survey of infections due multi-drug-resistant (MDR) C. striatum in South American countries remains necessary. This retrospective and prospective study aimed to analyze clinical-microbiological features of C. stri-atum clinical isolates from patients attended at a Brazilian tertiary care hospital, during a nine-year period. C. striatum strains (n=130) were isolated from infected patients attended at twenty nosocomial wards, mainly of tracheal aspirate (n=53) and blood and/or intravenous catheter (n=21/n=13). Notably, original cases of nosocomial infections due to C. striatum were verified in children making use of invasive devices, includ-ing one fatal neonatal case, in addition to a fatal respiratory infection in patient with cystic fibrosis, as well as urinary tract infections of kidney transplant recipients. Most of C. striatum strains expressed MDR profiles (88.46%). Emergence of vancomycin (1.90%) and linezolid (7.41%) resistance was verified among MDR and non-MDR-strains. In conclusion, endemic condition with wide dissemination among hospital wards of varied types of infections due to MDR and non-MDR C. striatum strains expressing heterogenic virulence potential and genetic features may occur in hospital units.</p>}, number={2}, journal={Ïã¸ÛÁùºÏ²Ê¿ª½±½á¹û}, author={F. Silva, Cecília Maria and F. Mota, Higor and de O. Cabra, Felipe and V. Farias, Yuri and M. Dimas, Stefany and S. de Santana, Giorgio and N. M. de Gusmão, Letícia and A. Nogueira, Bárbara and N. Ramos, Juliana and de Souza, Monica Cristina and de S. Leão, Robson and G. de Oliveira, Marcus Vinícius and S. dos Santos, Louisy and Mattos-Guaraldi, Ana Luíza and de Souza, Cassius}, year={2022}, month={Jan.}, pages={114–128} }