TY - JOUR AU - Silvia Thees Castro, AU - Jos茅 Augusto A. Pereira, AU - Eduardo A. R. de Castro, PY - 2023/11/01 Y2 - 2024/10/12 TI - Letter to the editor: The challenge of carbapenem resistance JF - 香港六合彩开奖结果 JA - BJHBS VL - 22 IS - 2 SE - Letters to the Editor DO - 10.12957/bjhbs.2023.80042 UR - /bjhbs/article/view/156 SP - AB - <p><span data-contrast="none">The global resistance of microorganisms to antimicrobials is one of the biggest public health challenges in recent decades however, among Gram-negative microorganisms, this problem has become very relevant, resulting in a shortage of medicines for the treatment of infections caused by these multi-resistant bacterial agents.</span><span data-ccp-props="{&quot;134245417&quot;:false,&quot;201341983&quot;:0,&quot;335559731&quot;:708,&quot;335559739&quot;:0,&quot;335559740&quot;:360}">聽</span><span data-contrast="none">Knowing the evolution of this resistance, among microorganisms in the hospital environment, is essential for: the projection of resistance in the coming decades, the rational use of antimicrobials and the adoption of measures to minimize their impact in this scenario.聽</span><span data-contrast="none">The most modern antimicrobial agents, which act on multi-resistant bacteria, are expensive, making their availability and use even more difficult, especially in the public health network in developing countries. However, new drugs for treating multidrug-resistant infections, due to their high cost, are often not available.</span><span data-ccp-props="{&quot;134245417&quot;:false,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:0,&quot;335559740&quot;:360}">聽</span></p> ER -