TY - JOUR AU - H. S. B. Junior, Paulo AU - C. C. Farias, Lucas AU - P. Oliveira, Sara AU - V. Perlingeiro, Raiele AU - C. Henrique, Stephany AU - C. Coelho-Oliveira, Ana AU - C. S谩-Caputo, Dan煤bia AU - F. Ferreira-Souza, Luiz AU - Bernardo-Filho, Mario PY - 2023/01/03 Y2 - 2024/10/12 TI - The anti-inflammatory effect of propolis on human tissue: A systematic review JF - 香港六合彩开奖结果 JA - BJHBS VL - 21 IS - 2 SE - Original Articles DO - 10.12957/bjhbs.2022.71605 UR - /bjhbs/article/view/3 SP - 91-100 AB - <p>Introduction: The healing process that occurs after a tissue lesion&nbsp;is divided into three distinct phases: inflammation phase,&nbsp;proliferation, and remodeling. Despite the structural similarity&nbsp;of the anatomy of the skin and oral mucosa, the oral mucosa&nbsp;presents a unique healing environment. Treatment options for&nbsp;chronic lesions are still limited, hence efforts in the research of&nbsp;traditional therapies with alternative clinical treatments, such&nbsp;as the use of propolis, have been conducted. Objectives: This&nbsp;systematic review aims to evaluate the anti-inflammatory&nbsp;property of propolis in the tissue repair process. Methods: A database&nbsp;search was performed using the descriptors 鈥淧ropolis鈥,&nbsp;鈥淲ound Healing鈥 and 鈥淐omplementary Therapies鈥. Results:&nbsp;Ninety-three publications were found in electronic databases.&nbsp;Of these 93 articles, 84 were excluded for failing to meet the&nbsp;eligibility criteria and only 9 articles were read in full. With&nbsp;regard to design, seven works were considered to be of 鈥渇air鈥&nbsp;methodological quality and two considered to be 鈥減oor鈥.&nbsp;Only one study was classified as Level of evidence III-2, three&nbsp;studies as III-3, and five studies as IV, due to the studies having&nbsp;been carried out without specific interventions. Conclusions:&nbsp;The benefits of propolis can be considered to be its proven&nbsp;anti-inflammatory activity, as well as collagen stimulation,&nbsp;rapid promotion of the healing process, and few side effects.</p> ER -