  TY  - JOUR
AU  - F. Silva, Cec铆lia Maria
AU  - F. Mota, Higor
AU  - de O. Cabra, Felipe
AU  - V. Farias, Yuri
AU  - M. Dimas, Stefany
AU  - S. de Santana, Giorgio
AU  - N. M. de Gusm茫o, Let铆cia
AU  - A. Nogueira, B谩rbara
AU  - N. Ramos, Juliana
AU  - de Souza, Monica Cristina
AU  - de S. Le茫o, Robson
AU  - G. de Oliveira, Marcus Vin铆cius
AU  - S. dos Santos, Louisy
AU  - Mattos-Guaraldi, Ana Lu铆za
AU  - de Souza, Cassius
PY  - 2022/01/04
Y2  - 2024/10/12
TI  - Multiresistance and endemic status of Corynebacterium striatum associated with nosocomial infections: a critical situation in Intensive Care Units and varied wards of a tertiary care hospital, Rio de Janeiro metropolitan area, Brazil
JF  - 香港六合彩开奖结果
JA  - BJHBS
VL  - 20
IS  - 2
SE  - Original Articles
DO  - 10.12957/bjhbs.2021.63963
UR  - /bjhbs/article/view/34
SP  - 114-128
AB  - &lt;p&gt;Nowadays, Corynebacterium striatum has been reported as etiologic agent of mild to severe hospital-acquired infections, including patients undergoing endotracheal intubation with fatal outcome. A continuous survey of infections due multi-drug-resistant (MDR) C. striatum in South American countries remains necessary. This retrospective and prospective study aimed to analyze clinical-microbiological features of C. stri-atum clinical isolates from patients attended at a Brazilian tertiary care hospital, during a nine-year period. C. striatum strains (n=130) were isolated from infected patients attended at twenty nosocomial wards, mainly of tracheal aspirate (n=53) and blood and/or intravenous catheter (n=21/n=13). Notably, original cases of nosocomial infections due to C. striatum were verified in children making use of invasive devices, includ-ing one fatal neonatal case, in addition to a fatal respiratory infection in patient with cystic fibrosis, as well as urinary tract infections of kidney transplant recipients. Most of C. striatum strains expressed MDR profiles (88.46%). Emergence of vancomycin (1.90%) and linezolid (7.41%) resistance was verified among MDR and non-MDR-strains. In conclusion, endemic condition with wide dissemination among hospital wards of varied types of infections due to MDR and non-MDR C. striatum strains expressing heterogenic virulence potential and genetic features may occur in hospital units.&lt;/p&gt;
ER  -