TY - JOUR AU - F. D. Batista, Saulo AU - V. de Melo, Karina AU - Horn, Patricia AU - da C. Lisboa, Vinicius AU - Cypriano, Ana Sheila AU - Pires, Andrea AU - de M. Ribeiro-Carvalho, Marilza AU - Santiago, F谩bio AU - F. O. de Souza, Maria Helena PY - 2021/01/04 Y2 - 2024/10/12 TI - Pulmonary and central nervous system infiltration of chronic lymphocytic leukemia with concomitant diffuse large B-cell lymphoma: Case report and review of literature JF - 香港六合彩开奖结果 JA - BJHBS VL - 19 IS - 2 SE - Literature Review DO - 10.12957/bjhbs.2020.59716 UR - /bjhbs/article/view/78 SP - 124-129 AB - <p>Introduction: Diffuse large B-cell lymphoma (DLBCL) and chronic lymphoid leukemia (CLL) are lymphoproliferative diseases of B lymphocytes. Objective: To describe the con-comitance of diseases with pulmonary and CNS involvement. Clinical case: A 67-year-old patient with DLBCL and CLL obtained partial remission of the diseases after six cycles of standard combined chemotherapy. Relapse of CLL (del17p; TP53+) occurred after 22 months, becoming refractory to a new treatment. Monoclonal B lymphocyte infiltration was found in the cerebrospinal fluid and bronchoalveolar lavage, leading to death due to respiratory failure. Conclusion: The unfavorable outcome shows a rare and serious complication in the concomitance of these diseases.</p> ER -